Making sure corrections don't vanish online

Making sure late endosomes are on time

Early endosomes collect and sort cargoes before maturing into late endosomes that ferry those cargoes to the lysosome. Liu et al. identify two proteins that spur early endosomes to transform and thus help ensure that cellular deliveries occur on schedule (1). As an early endosome morphs into a late endosome, it revamps its molecular composition. Early endosomes carry the GTPase Rab5, which attr...

Not a Sure Thing: Making Regulatory Choices

Making Corrections to Your Proof

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Obstacle avoidance during online corrections.

The dorsal visual stream codes information crucial to the planning and online control of target-directed reaching movements in dynamic and cluttered environments. Two specific dorsally mediated abilities are the avoidance of obstacles and the online correction for changes in target location. The current study was designed to test whether or not both of these abilities can be performed concurren...

Commentary: Sure I'm Sure: Prefrontal Oscillations Support Metacognitive Monitoring of Decision Making